4,447 research outputs found
Rickettsial pathogens and their arthropod vectors.
Rickettsial diseases, important causes of illness and death worldwide, exist primarily in endemic and enzootic foci that occasionally give rise to sporadic or seasonal outbreaks. Rickettsial pathogens are highly specialized for obligate intracellular survival in both the vertebrate host and the invertebrate vector. While studies often focus primarily on the vertebrate host, the arthropod vector is often more important in the natural maintenance of the pathogen. Consequently, coevolution of rickettsiae with arthropods is responsible for many features of the host-pathogen relationship that are unique among arthropod-borne diseases, including efficient pathogen replication, long-term maintenance of infection, and transstadial and transovarial transmission. This article examines the common features of the host-pathogen relationship and of the arthropod vectors of the typhus and spotted fever group rickettsiae
The Two-Dimensional S=1 Quantum Heisenberg Antiferromagnet at Finite Temperatures
The temperature dependence of the correlation length, susceptibilities and
the magnetic structure factor of the two-dimensional spin-1 square lattice
quantum Heisenberg antiferromagnet are computed by the quantum Monte Carlo loop
algorithm (QMC). In the experimentally relevant temperature regime the
theoretically predicted asymptotic low temperature behavior is found to be not
valid. The QMC results however, agree reasonably well with the experimental
measurements of La2NiO4 even without considering anisotropies in the exchange
interactions.Comment: 4 Pages, 1 table, 4 figure
QCD as a Quantum Link Model
QCD is constructed as a lattice gauge theory in which the elements of the
link matrices are represented by non-commuting operators acting in a Hilbert
space. The resulting quantum link model for QCD is formulated with a fifth
Euclidean dimension, whose extent resembles the inverse gauge coupling of the
resulting four-dimensional theory after dimensional reduction. The inclusion of
quarks is natural in Shamir's variant of Kaplan's fermion method, which does
not require fine-tuning to approach the chiral limit. A rishon representation
in terms of fermionic constituents of the gluons is derived and the quantum
link Hamiltonian for QCD with a U(N) gauge symmetry is expressed in terms of
glueball, meson and constituent quark operators. The new formulation of QCD is
promising both from an analytic and from a computational point of view.Comment: 27 pages, including three figures. ordinary LaTeX; Submitted to Nucl.
Phys.
Frogs (Coqui Frogs, Greenhouse Frogs, Cuban Tree Frogs, and Cane Toads)
Amphibians are perhaps most well known for their highly threatened status, which often masks appreciation for the great numbers of species that are widespread global invaders (Kraus 2009). Both purposeful and accidental introductions of amphibians have occurred worldwide. Motivations for purposeful amphibian introductions include their use as biocontrol agents and culinary ambitions (Storer 1925; Kraus 2009). However, there are an increasing number of amphibians that are being accidentally introduced and becoming widespread (Kraus 2009). These introductions are in some ways more disconcerting because they may be the most difficult to prevent in the future.
There are 19 nonnative amphibians that have become successfully established in 28 of the 50 U.S. states (Figure 9.1; Kraus 2009). The most successful non-native amphibian is the bullfrog (Lithobates catesbeianus), which has become established in 19 states outside of its native range on the eastern side of the United States, followed by the Cuban greenhouse frog (Eleutherodactylus planirostris), which has established itself in six states, and five frog species, including the Puerto Rican coqui (E. coqui), which are now established in three states outside of their native range (Figure 9.1; Kraus 2009). The state with the most nonnative frogs is California with eight species, followed by Hawaii with six, and Florida and Arizona with four (Table 9.1; Kraus 2009). Many nonnative amphibians in the United States, particularly in the western United States, are from other parts of the United States, namely, east of the Mississippi River. However, there are also many nonnative amphibians with tropical or subtropical origins that are primarily successful in tropical and subtropical states, such as Florida and Hawaii, and territories, such as Guam
Kosterlitz-Thouless Universality in a Fermionic System
A new extension of the attractive Hubbard model is constructed to study the
critical behavior near a finite temperature superconducting phase transition in
two dimensions using the recently developed meron-cluster algorithm. Unlike
previous calculations in the attractive Hubbard model which were limited to
small lattices, the new algorithm is used to study the critical behavior on
lattices as large as . These precise results for the first time
show that a fermionic system can undergo a finite temperature phase transition
whose critical behavior is well described by the predictions of Kosterlitz and
Thouless almost three decades ago. In particular it is confirmed that the
spatial winding number susceptibility obeys the well known predictions of
finite size scaling for and up to logarithmic corrections the pair
susceptibility scales as at large volumes with for .Comment: Revtex format; 4 pages, 2 figure
New Experimental limit on Optical Photon Coupling to Neutral, Scalar Bosons
We report on the first results of a sensitive search for scalar coupling of
photons to a light neutral boson in the mass range of approximately 1.0
milli-electron volts and coupling strength greater than 10 GeV using
optical photons. This was a photon regeneration experiment using the "light
shining through a wall" technique in which laser light was passed through a
strong magnetic field upstream of an optical beam dump; regenerated laser light
was then searched for downstream of a second magnetic field region optically
shielded from the former. Our results show no evidence for scalar coupling in
this region of parameter space.Comment: pdf-file, 10 pages, 4 figures, submitted to Physical Review Letter
Duality, thermodynamics, and the linear programming problem in constraint-based models of metabolism
It is shown that the dual to the linear programming problem that arises in
constraint-based models of metabolism can be given a thermodynamic
interpretation in which the shadow prices are chemical potential analogues, and
the objective is to minimise free energy consumption given a free energy drain
corresponding to growth. The interpretation is distinct from conventional
non-equilibrium thermodynamics, although it does satisfy a minimum entropy
production principle. It can be used to motivate extensions of constraint-based
modelling, for example to microbial ecosystems.Comment: 4 pages, 2 figures, 1 table, RevTeX 4, final accepted versio
The solution space of metabolic networks: producibility, robustness and fluctuations
Flux analysis is a class of constraint-based approaches to the study of
biochemical reaction networks: they are based on determining the reaction flux
configurations compatible with given stoichiometric and thermodynamic
constraints. One of its main areas of application is the study of cellular
metabolic networks. We briefly and selectively review the main approaches to
this problem and then, building on recent work, we provide a characterization
of the productive capabilities of the metabolic network of the bacterium E.coli
in a specified growth medium in terms of the producible biochemical species.
While a robust and physiologically meaningful production profile clearly
emerges (including biomass components, biomass products, waste etc.), the
underlying constraints still allow for significant fluctuations even in key
metabolites like ATP and, as a consequence, apparently lay the ground for very
different growth scenarios.Comment: 10 pages, prepared for the Proceedings of the International Workshop
on Statistical-Mechanical Informatics, March 7-10, 2010, Kyoto, Japa
Evidence for equilibrium iron isotope fractionation by nitrate-reducing iron(II)-oxidizing bacteria
Iron isotope fractionations produced during chemical and biological Fe(II) oxidation are sensitive to the proportions and nature of dissolved and solid-phase Fe species present, as well as the extent of isotopic exchange between precipitates and aqueous Fe. Iron isotopes therefore potentially constrain the mechanisms and pathways of Fe redox transformations in modern and ancient environments. In the present study, we followed in batch experiments Fe isotope fractionations between Fe(II)_(aq) and Fe(III) oxide/hydroxide precipitates produced by the Fe(III) mineral encrusting, nitrate-reducing, Fe(II)-oxidizing Acidovorax sp. strain BoFeN1. Isotopic fractionation in ^(56)Fe/^(54)Fe approached that expected for equilibrium conditions, assuming an equilibrium Δ^(56)Fe_(Fe(OH)3–Fe(II)aq) fractionation factor of +3.0‰. Previous studies have shown that Fe(II) oxidation by this Acidovorax strain occurs in the periplasm, and we propose that Fe isotope equilibrium is maintained through redox cycling via coupled electron and atom exchange between Fe(II)_(aq) and Fe(III) precipitates in the contained environment of the periplasm. In addition to the apparent equilibrium isotopic fractionation, these experiments also record the kinetic effects of initial rapid oxidation, and possible phase transformations of the Fe(III) precipitates. Attainment of Fe isotope equilibrium between Fe(III) oxide/hydroxide precipitates and Fe(II)_(aq) by neutrophilic, Fe(II)-oxidizing bacteria or through abiologic Fe(II)_(aq) oxidation is generally not expected or observed, because the poor solubility of their metabolic product, i.e. Fe(III), usually leads to rapid precipitation of Fe(III) minerals, and hence expression of a kinetic fractionation upon precipitation; in the absence of redox cycling between Fe(II)_(aq) and precipitate, kinetic isotope fractionations are likely to be retained. These results highlight the distinct Fe isotope fractionations that are produced by different pathways of biological and abiological Fe(II) oxidation
Ultrafast supercontinuum spectroscopy of carrier multiplication and biexcitonic effects in excited states of PbS quantum dots
We examine the multiple exciton population dynamics in PbS quantum dots by
ultrafast spectrally-resolved supercontinuum transient absorption (SC-TA). We
simultaneously probe the first three excitonic transitions over a broad
spectral range. Transient spectra show the presence of first order bleach of
absorption for the 1S_h-1S_e transition and second order bleach along with
photoinduced absorption band for 1P_h-1P_e transition. We also report evidence
of the one-photon forbidden 1S_{h,e}-1P_{h,e} transition. We examine signatures
of carrier multiplication (multiexcitons for the single absorbed photon) from
analysis of the first and second order bleaches, in the limit of low absorbed
photon numbers (~ 10^-2), at pump energies from two to four times the
semiconductor band gap. The multiexciton generation efficiency is discussed
both in terms of a broadband global fit and the ratio between early- to
long-time transient absorption signals.. Analysis of population dynamics shows
that the bleach peak due to the biexciton population is red-shifted respect the
single exciton one, indicating a positive binding energy.Comment: 16 pages, 5 figure
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